Identification and characterization of hundreds of potent and selective inhibitors of Trypanosoma brucei growth from a kinase-targeted library screening campaign.

In the interest of identification of new kinase-targeting chemotypes for target and pathway analysis and drug discovery in Trypanosomal brucei, a high-throughput screen of 42,444 focused inhibitors from the GlaxoSmithKline screening collection was performed against parasite cell cultures and counter-screened against human hepatocarcinoma (HepG2) ce

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Eastern Caribbean Circulation and Island Mass Effect on St. Croix, US Virgin Islands: A Mechanism for Relatively Consistent Recruitment Patterns.

The northeastern Caribbean Sea is under the seasonal influence of the Trade Winds but also of the Orinoco/Amazon freshwater plume.The latter is responsible for intensification of the Caribbean Current in general and of its eddy activity in the northern part of the Caribbean Sea.More importantly, we show in this study that the Center Console Cover f

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Investigation on A-FNS neutron spectrum monitor system

We proposed the neutron spectrum measurement system for Advanced Fusion Neutron Source (A-FNS).It is configured with fission chambers, Self-Powered Neutron Detectors, neutron activation systems using water flow, and activation monitors.In this study, we mainly investigated Puzzles the multiple activation foils which are sensitive to high energy neu

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